ZOVIRAX® Ointment/ZOVIRAX® Cream


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ZOVIRAX^® Ointment Full Prescribing Information

ZOVIRAX^® Cream Full Prescribing Information

Important Safety Information

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ZOVIRAX^® Ointment for Initial Genital Herpes Outbreak

ZOVIRAX^® (acyclovir) Ointment 5% is indicated in the management of initial genital herpes and in limited non–life-threatening mucocutaneous herpes simplex virus infections in immunocompromised patients.

Important Safety Information

ZOVIRAX^® Ointment is intended for cutaneous use only and should not be used in the eye. Mild pain (including transient burning and stinging) has been reported at an incidence comparable to placebo (30%). ZOVIRAX^® Ointment does not prevent the transmission of HSV infections and should not be used for the prevention of recurrent HSV infections.

ZOVIRAX^® Ointment is available by prescription only.

Please click here for full Prescribing Information.

ZOVIRAX^® Cream for Recurrent Cold Sores

ZOVIRAX^® (acyclovir) Cream 5% is indicated for the treatment of recurrent herpes labialis (cold sores) in adults and adolescents (12 years of age and older).

Important Safety Information

ZOVIRAX^® Cream is intended for cutaneous use only and should not be used in the eye or inside the mouth or nose. ZOVIRAX^® Cream has a potential for irritation and contact sensitization. In clinical trials, the most common adverse reactions at the site of topical application occurred in less than 1% of patients and included dry lips, desquamation, dryness of skin, cracked lips, burning skin, pruritus, flakiness of skin, and stinging on skin. ZOVIRAX^® Cream does not prevent transmission of HSV infections, and its effect has not been established in immunocompromised patients.

ZOVIRAX^® Cream is available by prescription only.

Please click here for full Prescribing Information.

This site is intended for healthcare professionals within the United States only.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

References: 1. Corey L, Benedetti JK, Critchlow CW, et al. Double-blind controlled trial of topical acyclovir in genital herpes simplex virus infections. Am J Med. 1982;73(1A):326-334. 2. Zovirax Cream 5% [prescribing information]. Bridgewater, NJ: CORIA Laboratories; 2009. 3. Spruance SL, Nett R, Marbury T, Wolff R, Johnson J, Spaulding T; for the Acyclovir Cream Study Group. Acyclovir cream for treatment of herpes simplex labialis: results of two randomized, double-blind, vehicle-controlled, multicenter clinical trials. Antimicrob Agents Chemother. 2002;46(7):2238-2243. 4. Custom cold sore survey. Princeton, NJ: Multi Sponsor Surveys Inc; December 2009. 5. Valtrex Caplets [prescribing information]. Research Triangle Park, NC: GlaxoSmithKline; 2008. 6. Barbarash RA. Update on treatments for oral herpes simplex viral infections (cold sores and fever blisters). Today’s Ther Trends. 2001;19:39-58.

ZOVIRAX is a registered trademark of GlaxoSmithKline.
©2012 CORIA Laboratories, a division of Valeant Pharmaceuticals North America LLC.

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